The only thing we ever have seen any evidence of value and THAT not definitive is in malabsorptive Bariatric Surgery. BUT why are you blathering when the preventive Tool was removed 20+ years ago with WH study and Estrogens. And PROVEN FALSE! (See Makary, BLIND SPOTS). Be real and honest or you are off my list.

hi guys LOVE your podcast. helps make me sound smart on rounds with the team. can i ask when or if you will ever address what to me is the huge elephant in the room for Evidenced Based Medicine - TPA! As you know there is a huge divide between the EM and Neurology community but most other doctors just assume that this therapy is well researched and very beneficial. Thanks for all that you do!

Great podcast. I am a PA student and have listend to every episode. I will be teaching a lecture to the new students next summer about evidence based medicine, all of which I learned from the podcast. I nearly broked out in laughter when a neurologist giving a recent lecture referred to blood pressure as the silent killer.

Just a great way to keep up on evidence-based family practice medicine. The premium version is worth it!

One of my favorite medical podcasts. Always worthwhile.

Love every other second of the show.

Great podcast. Really helpful in my pharmacy practice. All pharmacist should listen to this.

As a pharmacy student, I've found these podcasts to be very informative and have helped supplement information learned from class. Would definitely recommend this podcast!

Love, love your podcast & since discovering, have been recommending to pharmacy students/residents/co-workers. I wish more people in U.S. knew about your podcast. I know you said albuminuria is a future on your list. Others that I'd love to hear: 1) hypertriglyceridemia -- how to treat & what's real risk of pancreatitis 2) statins & CKD 4-5. Keep up the great work! --Beth, pharmacist, San Diego VA

I continue to learn something new every time I listen; for example in podcast 148 I found out Dr Mike Allen is an avid Family Guy fan (he tried to claim he only watched "occasionally" the cardinal sign of a Family Guy addiction) . And in the same podcast he made a reference to Homer Simpson. That has to be a first for a medical podcast- two references to prime time animated comedies. Keep up the good work.

I love this podcast and accompanying site. James and Mike make complex subjects understandable and make me laugh. (with them) As a pharmacist doing critical appraisal for our institution and how to best use our limited resources here in the Public Health Service, I appreciate the help this podcast offers. Thanks guys and keep them coming! I subject our students and residents to these and they usually thank me. Rob Boyle Arizona

Some say that "laughter is the best medicine". Such an allegation would be challenged by this podcast asking for evidence that this is true! And they would do so in a way that makes you laugh! Seriously, the hosts take information about drugs that is usually given to us in "sound bites" and dissect it by looking at the underlying science supporting claims. Without cynicism, they give a healthy, questioning view of what we often take for granted on a prescription. They also are offering an app for iPad called "MyStudies" that helps extract actual data from major drug studies allowing us to judge benefits and risks of meds for ourselves. Outstanding!

Evidence-based drug therapy made practical and fun...and SEXY!!!

This podcast helps keep me up to date with the latest literature and has helped me learn to analyze it. It is fantastic even though the hosts are canadian. No but seriously this is excellent and I listen toit on the way to the hospital often. It has helped me in moreways than I can count and should be mandatory on every clinicians ipod.

Great review of the evidence for medical intervention. Also, a really nice discussion of how to apply literature to your practice.

Each episode there's something interesting to learn, and it's presented in the most entertaining way! I wish there were more medical podcasts this enjoyable, but so far I haven't found any that measure up to this standard.

James and Mike do a super job getting to the nuts and bolts of every issue and giving physicians actionable information. The data they have presented has either reinforced my practice or encouraged me to change because I have a better handle on the evidence. The podcasts are just the right length to get you through your morning workout!

Great stuff to listen to and learn accurate information. I love it how it has humor. Humor also makes it interesting and makes me look forward to what comedic comment comes next. Makes me remember it better lol... I'm a Family Nurse Practitioner student and this is great for primary care in addition to some other podcasts. Now that you can get CME from this, its even better and it shows that this is legit!

Great podcast - they take a topic that not everybody is crazy about - evidence-based medicine - and present it in an interesting and informative way. Unlike a lot of other medical podcasts, this isn't just somebody reading abstracts for half an hour but rather a back and forth discussion between a family doctor and a pharmacist. Sort of like Car-Talk without the humor.... well, they try to be funny sometimes. The discussion format really makes it much more listenable compared to most podcasts. There is an EBM slant here - if somebody didn't do a study showing that gravity does indeed exist, I'm not sure they'd believe in it - but definitely a well-planned, well-executed series. A must-listen for any medical student or resident. Incidentally, a careful listener may notice subtle differences between the practice of medicine in Canada and here in the US, which is always good food for thought as well.

TECH podcasts are of high quality. The reliance on pharma research is a bit disturbing (that was sarcasm).

Love, love , love everything about you! Thank you! You rock !!!

These podcasts will improve your practice and your patients lives. In the meantime, it will make your head spin and question everything you know. Fun to listen to at any time.

Evidenced based drug therapy made practical and fun says it all. What Mike & James key in on that others seem to miss how to utilize patient-oriented evidence in concert with the patient's values & preferences. Kudos and a must listen for any practitioner or educator of evidence based medicine. Now if we can only get those writing the guidelines to tune in.

I'm a nurse practitioner student who was looking for something edifying for my long commutes to clinic. The pragmatic, funny, and evidence-based discussions these two provide help to solidify what I'm learning and give a great real-life perspective. I hope you two continue with this project!

No misrepresentations here - the podcast delivers as promised. 1) evidence made practical, and 2) "fun" (a humorous slant recognizing we don't know what we don't know). I recommend this to all of my fellow residents in training, as well as medical students, pharm.d candidates, and the senior internists and pharmacists who work in our graduate medical education programs here in Michigan. I'd gladly pay for the content, but for now cherish that it's freely available (and easily shared for that matter). Thanks James, Mike!

As a pharmacy student in the United States I find these podcasts to be very informative and educational. They offer evidence based medicine which can at times be missed during the educational process. I find that these podcasts supplement very well with much of the 'mechanistic' medicine being taught and offers the viewpoint of what is actually seen in practice. They also help to clarify guidelines through evidence which is helpful when at times in the educational process it can appear that we as students are to take the guidlines as gospel. Overall great podcast that offers an interesting, informative, and sometimes comical view of evidence based drug therapy.

I have been in practice for 18 yrs and have learned more in these podcasts than from any other source. It has drastically changed the way I prescribe medications. I can honestly say that I use their evidence-based guidance at least 5 times a day when choosing medications for patients, or choosing not to treat based on the data they have presented. And to top it off they are humorous, at least as funny as Canadians can be.

As an older US med student in my clinical years I like to begin the day with a cup of coffee and a perusal of the latest podcasts. Therapeutics Initiative is an excellent co-dependency (Yet another misapplication of DSM 4.0). Its a fun listen with enough thought-provoking comments to stimulate one's curiosity and sufficient references to provide avenues for further investigation. Special thanks for the Christmas bonus - medical myths are a great framework for the importance and limitations of EBM...and Doctors McCormack, Allan and their imaginary friend Dr Bob can all tell their kids how they are reaching across international borders to help students as far away as Memphis, Tennessee...the buckle in the "stroke belt." Thanks again.

I first learned of the Therapeutics Initiative several years ago, after following a link from Dr. Jon Abramson's website, the author of the 2004 book "Overdosed America." As a family doctor in the midwestern US, I find the TI podcast to be a breath of fresh air and an antidote to the pervasive influence of drug company marketing - from television ads for the "latest greatest" to the glossy ads which seem to comprise the better part of each month's issue of my professional association's journal. Thanks for keeping us grounded.

This is great fun and highly informative. I coordinate the evidence-based medicine curriculum in our Family Medicine residency, and these sessions reinforce what I teach the residents. It's great to have this as a resource. (and, it is like Click and Clack do Journal Club) Thanks again for the great work

Drs. McCormack and Allan are my primary source for unbiased medical information. They cut through the groupthink and media hype that cloud public perceptions of health issues. James and Mike are not afraid to admit that a lot of common medical advice is based on hunches and theories -- and when evidence suggests doing something different, they tell us. This program is invaluable for a layman who wants to make his or her own decisions about the risks and benefits of various medical treatment options. Besides that, these guys are entertaining!

This weekly podcast with a pharmacist and physician provides excellent insights into use of medications, from the perspective of evidence-based medicine. These guys have clinical practices and are also well grounded in the medical literature, so they can provide useful and practical information that clinicians can use to improve care to patients. They also have great chemistry together and inject humor to keep things lively and interesting. Highly recommended!