Big Brains

334
Science #146

Big Brains explores the groundbreaking research and discoveries that are changing our world. In each episode, we talk to leading experts and unpack their work in straightforward terms. Interesting conversations that cover a gamut of topics from how music affects our brains to what happens after we die.

Recent Episodes
  • Can You Really Die of a Broken Heart? The Hidden Dangers of Grief, with Mary Frances O'Connor
    Apr 3, 2025 – 00:31:58
  • The Science Behind Raising Successful Kids, with Ariel Kalil
    Mar 20, 2025 – 00:31:19
  • Do Animals Understand Death?, with Susana Monsó
    Mar 6, 2025 – 00:31:58
  • Why Measles Is Resurging—And The Rise Of Vaccine Hesitancy, with Adam Ratner
    Feb 20, 2025 – 00:35:03
  • The Little-Known Secrets To A Good Life, with Shigehiro Oishi
    Feb 6, 2025 – 00:33:18
  • How Bioelectronics Could Heal Our Bodies And Minds, with Bozhi Tian
    Jan 23, 2025 – 00:29:17
  • Could A Fungal Pandemic Be “The Last of Us?", with Arturo Casadevall
    Jan 9, 2025 – 00:26:53
  • The "Magic Words" That Turn Resolutions Into Reality
    Jan 2, 2025 – 00:32:20
  • What’s The Truth About Alcohol’s Benefits And Risks? with Tim Stockwell
    Dec 19, 2024 – 00:32:37
  • What Happens When We Die? with Sam Parnia
    Dec 5, 2024 – 00:30:29
  • The Illusion of Moral Decline
    Nov 21, 2024 – 00:32:02
  • Can We Predict The Unpredictable? with J. Doyne Farmer
    Nov 14, 2024 – 00:33:14
  • Unlocking The Secrets Of ‘SuperAgers’, with Emily Rogalski
    Oct 31, 2024 – 00:22:33
  • 2024 Nobel Laureate Explains What Makes Countries Fail Or Succeed, with James A. Robinson
    Oct 17, 2024 – 00:29:13
  • Why Can’t Scientists Agree On The Age Of The Universe? with Wendy Freedman
    Oct 3, 2024 – 00:24:28
  • What Are We Getting Wrong About Young Voters?, with Cathy Cohen
    Sep 19, 2024 – 00:28:45
  • Why Are More Women Saying No To Having Kids? With Peggy O'Donnell Heffington
    Sep 5, 2024 – 00:32:04
  • How Homeownership Shaped Race In America, with Adrienne Brown
    Aug 22, 2024 – 00:27:23
  • Fighting Back Against AI Piracy, with Ben Zhao and Heather Zheng
    Aug 8, 2024 – 00:28:31
  • The Bioelectric Future of Regenerative Medicine
    Jul 25, 2024 – 00:28:23
  • Is Mindfulness The Secret To Health?
    Jul 11, 2024 – 00:33:42
  • Feeling Stuck? Here’s How To Achieve a Breakthrough, with Adam Alter
    Jun 27, 2024 – 00:33:51
  • What Makes Something Memorable (or Forgettable?) with Wilma Bainbridge
    Jun 13, 2024 – 00:26:33
  • Learning To Speak To Whales Using AI, with David Gruber
    May 30, 2024 – 00:26:06
  • Storm Warning: Why Hurricanes Are Growing Beyond Measure, with Michael Wehner
    May 16, 2024 – 00:27:34
  • How To Manifest Your Future Using Neuroscience, with James Doty
    May 2, 2024 – 00:31:20
  • Why We Die—And How We Can Live Longer, with Nobel Laureate Venki Ramakrishnan
    Apr 18, 2024 – 00:32:31
  • What Dogs Are Teaching Us About Aging, with Daniel Promislow
    Apr 4, 2024 – 00:32:30
  • Where Has Alzheimer’s Research Gone Wrong? with Karl Herrup
    Mar 21, 2024 – 00:29:05
  • Why Breeding Millions of Mosquitoes Could Help Save Lives, With Scott O'Neill
    Mar 7, 2024 – 00:30:43
  • Why Shaming Other Countries Often Backfires, with Rochelle Terman
    Feb 22, 2024 – 00:33:45
  • Can Trump Legally Be President?, with William Baude
    Feb 6, 2024 – 00:36:11
  • What Our Hand Gestures Reveal About Our Thoughts, with Susan Goldin-Meadow
    Jan 25, 2024 – 00:26:23
  • Psychedelics Without Hallucinations: A New Mental Health Treatment? with David E. Olson
    Jan 11, 2024 – 00:32:26
  • The Science Of Happiness
    Dec 28, 2023 – 00:29:55
  • Do We Really Have Free Will? With Robert Sapolsky
    Dec 14, 2023 – 00:34:37
  • A Radical Solution To Address Climate Change, with David Keith
    Nov 30, 2023 – 00:33:34
  • How PFAS “Forever Chemicals” Are Harming Our Health, with Linda Birnbaum
    Nov 16, 2023 – 00:29:01
  • Are We Worse People Than We Used To Be? With Adam Mastroianni
    Nov 2, 2023 – 00:31:32
  • Freakonomics’ Steven Levitt On The Secret To Making Tough Choices
    Oct 19, 2023 – 00:39:55
  • Will Political Violence Destroy Our Democracy?, With Robert Pape
    Oct 5, 2023 – 00:28:51
  • Defending Campus Free Speech In A Polarized Age, with Paul Alivisatos and Tom Ginsburg
    Sep 22, 2023 – 00:32:52
  • Why The Secret To Health Lies In The Mind-body Connection, with Ellen Langer
    Sep 7, 2023 – 00:32:42
  • Phonics Vs. Whole Word: The Science Of Reading, With Adrian Johns
    Aug 24, 2023 – 00:34:30
  • How AI Is Transforming Scientific Research, With Rebecca Willett
    Aug 10, 2023 – 00:31:38
  • How AI Could Change The Law
    Jul 27, 2023 – 00:27:50
  • How AI Can Predict Future Scientific Discoveries
    Jul 20, 2023 – 00:29:21
  • The Uncovered History of Space Travel & Its Privatized Future
    Jul 13, 2023 – 00:28:34
  • The Health Costs of Air Pollution
    Jul 6, 2023 – 00:28:54
  • How Your Brain Benefits From Music, With Larry Sherman
    Jun 29, 2023 – 00:29:36
Recent Reviews
  • Kai'mana
    Well done
    Excellent topics and guests. Thoughtful, and thought provoking
  • Voles Rule
    Big Brains
    Excellent. Concise, informative, plausible and easy listening
  • Fe Ford
    My favorite podcast
    I want to know and learn everyone on this podcast. I love the learning. Great topics and discussions. Give me more.
  • Joy Jiang Chen
    Fascinating
    Fascinating study on what happens when we die. The researcher sums the end of the study well, but the question for me is what lives to save, certainly not those who die of untreatable diseases, right?
  • UofC Optimistic Sceptic
    Adrienne Brown Dissapointing
    In the most recent podcast I listened to, I got to hear Adrian Brown discuss whiteness in real estate in a way that shocked me that such “scholarship” exist on the campus of Universe Chicago. She is a perfect example of what is plaguing higher education today. Neo-Marxist thinking. Claiming wanting to own things is white. A basic principle of economics is utility. Property has utility. Everybody wants to maximize their utility.
  • Factory Rat
    Good and clear
    I found out about Paul Sereno on Milo Rossi’s Green Sahara episode and I followed him here to Big Brain. I will be back to learn more from this very well made podcast.
  • angst1963
    Big Brains
    This is a great show. Topics explored and explained in plain language. Always interesting material.
  • AlanCJ97
    Insightful
    Always something interesting and relevant to our times. One of my favorite podcasts
  • cinther055
    Science and research you can actually use
    Research that’s actually data-driven, in-depth and really rigorous!
  • muzakmaestro
    Wonderful pod!
    Very digestible interesting and informative - keep up the great work!
  • Royce1629
    Great show!
    It's informative, interesting, and approachable! A great way to communicate complicated science topics to people who are far busier than is probably good for us.
  • MikeyhePlumber
    #1 Podcast in the world
    Best Podcast I have listened to in a long time very informative and interesting!
  • CJ Niles
    Whales
    One of the first things that whales would probably say would be questions like why are we destroying the planet? Why are we killing their children?
  • Shauna NI
    More Dr. Doty
    Manifesting intentions was riveting! More of his research and thinking please. Shauna Hill
  • bork15
    What a gem!
    Ever curious about ANYTHING and want to learn about that topic from the leading researchers or experts on that field? Well this has been such a true gem and a fun listen. Kudos!
  • Mork342
    On Personalized Law through AI tools.
    Archie Bunker would love this idea — as long as the Christian cannons are the criteria. How an academically serious person can make the many suggestions that the professor provided is ridiculous. Now, … I have not read the book. If it is satirical in theme, Norman Lear would approve.
  • Tiglath
    August 10th issue on AI with Rebecca Willett
    The contents of the podcast (based on the transcript) would not be essentially altered if every use of the term “AI” were to be replaced by “statistics” (or perhaps “computational statistics”. The current state of the AI research field is that it is dominated by “statistical” methods, such as “machine learning” and “neural nets”. It is debatable whether “intelligence” is involved or is relevant to this work. There has clearly been a major “breakthrough” in modern statistics where the use of data structures and algorithms (e.g. neural nets and their training) has overshadowed the classical methods based on analytic functions (distributions). The use of “AI” in science should amount to use of these new, modern methods of statistical modeling. Use of “Large Language Models” and chatbots based on them should definitely be discouraged, in science as in medicine, law, or any other field where truth and accuracy and judgement are valued.
  • swinterroth
    Must subscribe podcast
    Big Brains podcast is an absolute must-listen for anyone interested in gaining insights into the minds of some of the most influential people in the world today. Each episode features in-depth interviews with top academics, experts, and researchers who share their expertise and experience on topics ranging from technology, science, politics, and much more. The podcast host, Paul Rand, is an incredible interviewer who knows how to ask thought-provoking questions that stimulate engaging and informative discussions. The guests are experts in their fields and share their knowledge in a way that is both accessible and fascinating. One of the standout features of Big Brains is its ability to make complex topics easy to understand. Whether you are an expert in the field or a curious listener, you will leave each episode with a better understanding of the topic and its relevance in today's world. Overall, I highly recommend the Big Brains podcast to anyone who wants to expand their knowledge and stay up to date with the latest trends and ideas in various fields. It is a must-listen for anyone who wants to engage in intelligent discussions and gain valuable insights from some of the brightest minds in the world."
  • LOL listener
    How the Food Industry Created Today’s Obesity Crisis, with Marion Nestle
    Thank you for a very funny (I hope not unintentionally) podcast interview with Marion Nestle. I had forgotten what prima donnas college professors could be. I loved it when the interviewer posited that nutrition advice had changed over time, only to be met with her answer, “I completely disagree”, followed by a reference to a 1950s study that said we should eat more fruits and vegetables and get enough sleep. Yep, conclusive proof that absolutely nothing has changed. So ridiculously funny. I also laughed when she suggested that the Internal Revenue Code should not allow food companies to deduct their marketing costs as business expenses. Hilarious. Wouldn’t we all be better off if food companies could only take tax deductions for expenses that Marion pre-approved? But my favorite was the interviewer’s last question when he asked Marion what we would see in her shopping cart if we could follow her through a grocery store. And she completely ignored the question other than to mention that she is entertained by the nutrition labels on food packages. Not as entertained as I was by her know-it-all haughtiness. Marion’s certainty in all things and disdain for others was for me, and I’m sure for many others who see the world as a place that is not starkly black or white, nothing less than comic genius. Thanks again.
  • darrylpablo
    Time well spent
    Since listening to one of the earliest podcasts on human evolution to a more recent one on the Good Life, I’ve consistently benefited from Big Brains’ meaningful curation and understanding of thought-provoking content and guests - and you will too. Thank you!
  • bradlet hh
    Great
    So refreshing to here novel ideas so clearly explained
  • LCOYSTER
    Fun show, good and thoughtful host
    I enjoy the breadth or topics this show covers and the thoughtful questions asked about the guests’ topics of expertise.
  • Gabriel240194a
    Great podcast, inspired me to apply to UChicago
    I had been listening to Big Brains for a while and I always liked their focus on research. It exposed me to professors and areas of focus of the University of Chicago and helped me develop a sense of belonging, that ultimately was a factor that motivated my application for a Master program at the Harris School of Public Policy. I really recommend this podcast!
  • irisalegmz
    Digestible Learning!
    Love short podcasts that give a lot of info and bring experts to share their experiences.
  • Funkyjia
    Inspired me to continue my education
    I was one of those smart high school student with no particular interest because I was interested in EVERYTHING but was depressed because I struggled to think of a possible career for myself. I remember the first time I was listening to this podcast in 2019. I was actually writing my college applications, one was for UChicago, and listening to experts on a variety of subjects excited me so much that I got even more confused on what I wanted to major in. At the same time, the interviewees were even more curious than me, and that was a reminder that it is a personal choice to explore outside of one’s career field, rather than limitations existing. So while Iearning about research that isn’t in textbooks yet, I was also getting a weekly reminder that I need to go further in education. Big Brains promotes reflection and limitless curiosity beyond the episodes. It is inspiring, informative, but also engaging. It treats bewilderment not as a weakness but as a renewable fuel. So, thank you, Big Brains, as you have changed my life.
  • Lady BeBe04
    Big Brains Podcast
    The different topics are very educational and interesting! The engaging of discussion of each topic has my attention! Please keep this going Paul Rand you are doing an amazing job!
  • CJT21122112
    Excellent content on Big Brains!
    Love listening to this podcast during my daily walks!
  • SJGreen1
    Outstanding content, brilliantly presented
    Each episode is filled with a genuinely novel idea that is presented by a genuinely brilliant thought leader. It is a joy to listen to and learn from and Paul Rand is a gifted host.
  • Bellow Chicago
    Great Podcast
    I always learn something new.
  • MCCMEX
    Great podcast
    Love this podcast; I never miss an episode
  • bruce1956andcounting
    Supreme Court podcast
    Not a thoughtful or academic podcast, but entirely political. It would be appropriate for a university to look at both sides of an issue like appointing Supreme Court Justices - or to have the intellectual integrity to acknowledge a bias. Disappointing.
  • Katgeary
    Love
    This podcast is always so thought provoking: it’s like quintessential cocktail chatter and helps push conversation always love the topics chosen.
  • Jonnyfyve
    Fantastic ideas that make you think!
    I adore the Big Brains podcast because the storytelling makes the research from Uchicago faculty come alive. The topics are often counter-intuitive and always illuminating! Joanie
  • lbenrey
    Well produced and dynamic
    I really enjoy Big Brains because of its content but also because it’s dynamic and plays clips and recordings that are relevant to what the speaker is talking about. It is very well produced and I appreciate that it is not just hearing two people talk.
  • dbcalex
    Informative, thought-provoking, approachable
    This is a great podcast that gets you thinking on a range of topics. The host has an approachable manner that gets his expert guests to open up like they are having a cup of coffee together. He also asks the questions that I would want to ask. The result is that listening to this podcast puts you on the campus of one of the world's leading education and research institutions.
  • mrstern312
    Top podcast
    Amazing guests. Thought provoking topics. A must-have on my playlist. Highly recommend Big Brains!
  • tylergchan
    Fresh insights
    For the last few years as a student at UChicago, I have listened to the Big Brains podcast and really enjoyed the freshness of the insights which the conversations bring out.
  • J2019!
    If You’re a Curious One...
    ... then this is the podcast for you. Each episode discusses the research of a different UChicago faculty member. The host Paul Rand has an incredible way of making the guests feel comfortable. Unlike in other academic podcasts, the research is described in a way that makes sense to the public, minus the jargon and minutiae. Even if you have no affiliation with the University of Chicago, this podcast is smart, fun, and interesting, and it satisfies my hunger for new ideas during my 30-minute drive to work.
  • Listentome cuzimgood
    A Cure for Boredom
    I like listening to podcasts when I’m bored or while multitasking and I have to say Big Brains has some of the best content I have come across. The podcasts are like surprises because they jump into all sorts of topics - many of which I have seldom thought of but that now make my brain tick.
  • fvirginia18
    Awesome!
    Great podcast! So many interesting topics! Anyone can find something!
  • Alchemy 1
    Fabulous podcast for the inquisitive mind
    This podcast is wonderful! Lots of different and interesting topics, by movers and shakers in the field.
  • Clubber0303
    Incredible!
    Great source a knowledge from a trustworthy source! Keep up the good work!
  • acero.s
    Would recommend
    Great content and great production.
  • Ron Schwieters
    Big Brains
    Thanks Uchicago for the great content.
  • Spooky Jones
    A really informative and engaging listen
    Big Brains covers a lot of topics, so it’s a really great way to get insight into a number of interesting issues. I feel just a tiny bit smarter after listening.
  • Berrt_123
    Great Series
    I love these podcasts. The diverse range of thoughts and speakers are truly enlightening and should inspire anyone who listens regularly.
  • lipechen
    Interesting podcast!
    I am fascinated with this podcast. Very informative!
  • lauter18
    My favorite to listen to
    So interesting! Well put together
  • LipiGee
    Great!
    Love this podcast!! Thanks for highlighting UChicago science :)
  • jordanporterwoodruff
    I love it!
    I absolutely love this podcast! It is very informational.
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